Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MCM3AP All Species: 5.76
Human Site: T1837 Identified Species: 12.67
UniProt: O60318 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60318 NP_003897.2 1980 218405 T1837 H R N W K R S T E C A Q E G R
Chimpanzee Pan troglodytes XP_525497 1981 218320 T1838 H R N W K R S T E C A Q E G R
Rhesus Macaque Macaca mulatta XP_001118009 1415 157213 G1278 W L K Q A V L G F Q L P Q M D
Dog Lupus familis XP_537925 1989 218752 V1846 H Q K G K R S V E R G P E G R
Cat Felis silvestris
Mouse Mus musculus Q9WUU9 1971 217122 K1828 V H Q K G K K K E E S G R E G
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514089 1519 168947 E1381 R K P G N G K E G R I P S A E
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_689234 2082 230356 Q1894 R D M N A E S Q R I G E Q T Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9U3V9 1370 158161 T1233 I K I L Q Y D T D D Y L N F V
Honey Bee Apis mellifera XP_395462 961 111706 I824 F Q T Q D G E I I S S L E K L
Nematode Worm Caenorhab. elegans NP_501328 1116 129063 R979 K C A L I E T R F K F D A P D
Sea Urchin Strong. purpuratus XP_795787 1945 218422 R1798 E K E E R R R R R A E E R L P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 69.1 83.7 N.A. 78.4 N.A. N.A. 53.8 N.A. N.A. 42.2 N.A. 21.3 20.6 21.3 25.4
Protein Similarity: 100 99.6 70.1 89.4 N.A. 85.5 N.A. N.A. 62.7 N.A. N.A. 58.5 N.A. 35.7 34.3 35.9 43
P-Site Identity: 100 100 0 53.3 N.A. 6.6 N.A. N.A. 0 N.A. N.A. 6.6 N.A. 6.6 6.6 0 6.6
P-Site Similarity: 100 100 6.6 60 N.A. 20 N.A. N.A. 6.6 N.A. N.A. 26.6 N.A. 26.6 20 6.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 19 0 0 0 0 10 19 0 10 10 0 % A
% Cys: 0 10 0 0 0 0 0 0 0 19 0 0 0 0 0 % C
% Asp: 0 10 0 0 10 0 10 0 10 10 0 10 0 0 19 % D
% Glu: 10 0 10 10 0 19 10 10 37 10 10 19 37 10 10 % E
% Phe: 10 0 0 0 0 0 0 0 19 0 10 0 0 10 0 % F
% Gly: 0 0 0 19 10 19 0 10 10 0 19 10 0 28 10 % G
% His: 28 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 10 0 10 0 0 10 10 10 10 0 0 0 0 % I
% Lys: 10 28 19 10 28 10 19 10 0 10 0 0 0 10 0 % K
% Leu: 0 10 0 19 0 0 10 0 0 0 10 19 0 10 10 % L
% Met: 0 0 10 0 0 0 0 0 0 0 0 0 0 10 0 % M
% Asn: 0 0 19 10 10 0 0 0 0 0 0 0 10 0 0 % N
% Pro: 0 0 10 0 0 0 0 0 0 0 0 28 0 10 10 % P
% Gln: 0 19 10 19 10 0 0 10 0 10 0 19 19 0 10 % Q
% Arg: 19 19 0 0 10 37 10 19 19 19 0 0 19 0 28 % R
% Ser: 0 0 0 0 0 0 37 0 0 10 19 0 10 0 0 % S
% Thr: 0 0 10 0 0 0 10 28 0 0 0 0 0 10 0 % T
% Val: 10 0 0 0 0 10 0 10 0 0 0 0 0 0 10 % V
% Trp: 10 0 0 19 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 0 0 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _